Observational studies and “real world” anesthesia pharmacoeconomics

Correct sampling in observational studies.

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Causal Inference in Anesthesia and Perioperative Observational Studies

Purpose of Review Observational studies are of great importance to anesthesia and perioperative care research, as they reflect routine clinical practice. However, because observational data are nonexperimental, assigning causality to identified relationships has a significant risk of bias. After describing the pros and cons of observational studies, we provide an overview of the different metho...

Smog, Cognition and Real-World Decision-Making

Cognitive functioning is critical as in our daily life a host of real-world complex decisions in high-stakes markets have to be made. The decision-making process can be vulnerable to environmental stressors. Summarizing the growing economic and epidemiologic evidence linking air pollution, cognition performance and real-world decision-making, we first illustrate key physiological and psychologi...

Pharmacoeconomics: Cost of Illness Studies

Cost-of-illness studies measure the economic burden of a disease and estimate the maximum amount that could potentially be saved or gained if a disease were to be eradicated. Direct medical costs and indirect costs are measured using top down and bottom up approaches Human Capital approach, Willingness-to-Pay (WTP) approach and Friction Costs approach respectively. The perspectives may measure ...

Targeted Literature Review of Medication Event Monitoring Systems to Evaluate Adherence in Observational Real-World Studies.